Analysis Note
ControlA431 Cell Lysate.
Application
Immunocytochemistry:
A 1:500 dilution from a representative lot detected Ebp1 in NIH/3T3, A431, and HeLa cells.
Research Sub CategoryRNA Metabolism & Binding ProteinsChromatin Biology
Anti-Ebp1 N-terminal Antibody is a Rabbit Polyclonal Antibody for detection of Ebp1 also known as Proliferation-associated protein 2G4 & has been validated in WB, ICC.
Research CategoryEpigenetics & Nuclear FunctionEpigenetics & Nuclear Function
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Ebp1 is an RNA-binding protein involved in growth regulation. In cancer cells, this protein and has been implicated in growth inhibition and differentiation. Ebp1 is known to bind ribosomal and double-stranded RNA. It is a found in pre-ribosomal ribonucleoprotein complexes and is believed to play a role in ribosome assembly and rRNA processing. This protein is also a component of cytoplasmic bcl-2 messenger ribonucleoprotein. Through interactions with histion deacetylases, this protein can act transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes. Ebp1 also interacts with the cytoplasmic domain of the ErbB3 receptor, potentially transducing regulatory growth signals.
Immunogen
Linear Peptide corresponding to the N-terminus of Ebp1.
Epitope: N-terminus
Linkage
Replaces: 07-397
Physical form
Rabbit Polyclonal Serum with 0.05% sodium azide
Unpurified
Quality
Evaluated by Western Blotting in A431 cell lysate.
Specificity
Recognizes Ebp-1.
Storage and Stability
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Target description
48 kDa Observed
This product has met the following criteria to qualify for the following awards: